CBD and Acne

What is acne?

According to the AAD American Academy of Dermatology Acne affects 80% of people between the ages of 18 and 30.  It is a condition of the skin characterized by the overproduction of sebum, the oil that coats the face and scalp of mammals.

The purpose of sebum is to carry dead cells to the surface and to waterproof and protect the skin. However, too much sebum is produced and it collects in the pores, preventing bacteria from escaping.

This blockage leads to inflammation and eventually infection, causing white blood cells to flood the area.  After a few days, dead white blood cells accumulate as pus and a pimple is formed.

Why Is CBD for acne so effective?

The root cause of the pathology of acne is not well understood but after a study was conducted by the Department of Physiology at the University of  Debrecen there is a clear correlation between endocannabinoid deficiency, meaning faulty endocannabinoid signalling, and the manifestation of various facets of acne.

Dr. Tomas Biro stated, “When the endocannabinoid system fails to function efficiently, it fails to regulate the cells in which the deficiency is occuring. In the case of acne, sebocytes in the skin appear to have low levels of endocannabinoid mRNA (the leftovers of genetic transcription), strongly suggests that acne could be a symptom of endocannabinoid system deficiency.”

So what does this mean for all us non doctors? Endocannabinoids, are fat-based molecules. Sebocytes (the cells which comprise the sebaceous glands) exist for the sole purpose of producing a fatty substance: sebum.

As sebum is produced, so are endocannabinoids. These endocannabinoids continuously activate cannabinoid receptors, which suppress the activity level of the cell (in this case, the activity is to produce sebum) to the appropriate level dictated by homeostasis. In cases of acne, there appears to be a significant correlation with underexpression of the endocannabinoid system. 

This study, carried out to determine whether or not topical CBD oil ointment was effective in treating acne, produced noteworthy results.  After two weeks of daily use, 100% of respondents – every single participant in the study, without exception – reported positive change in the expression of their condition.  60% experienced complete elimination of acne. Who knew (besides these smart scientists and doctors) that CBD was capable of such change?!?